The core game play remains the same, and each deck contains the same number of cards with the same note range as the original set. The main differences are that the Deluxe set: (1) includes level six instead of it being a separate purchase, (2) introduces new wildcards (play as any note value) and "take two" cards (give two cards from your hand to your opponent) that can optionally be added to any level, (3) is printed on real playing card stock so they're more durable and easier to shuffle, (4) has updated artwork with more vibrant colors, and (5) is packaged in a sturdy two piece box with dividers.